The arrest had taken place at the Rideetenna roadblock in Valaichchenai, Police Media Spokesperson DIG Ajith Rohana said.
The duo had been transporting 9,240 bottles of arrack in a lorry when the arrest took place.
It has been revealed that the stock of arrack is estimated to be worth around Rs 17 million.
The suspects are to be produced before the Valaichchenai Magistrate today.
Further investigations into the incident are currently underway.